Rabbit polyclonal antibody raised against synthetic peptide of ABCA1.
A synthetic peptide corresponding to amino acids 1100-1300 of human ABCA1.
Hamster, Human, Mouse, Rat
This antibody is specific to ABCA1.
Quality Control Testing:
Antibody Reactive Against Synthetic Peptide.
Flow Cytometry (1:200) Immunocytochemistry (1:200) Immunofluorescence (1:200) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200) Immunoprecipitation (1:500) Western Blot (1:500) The optimal working dilution should be determined by the end user.
In Tris-citrate, pH 7.0-8.0 (0.02% sodium azide)
Store at 4°C. Do not freeze.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency. [provided by RefSeq
ATP binding cassette transporter 1,ATP-binding cassette 1,ATP-binding cassette, sub-family A member 1,OTTHUMP00000021833,cholesterol efflux regulatory protein,membrane-bound