EGR2 polyclonal antibody
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of EGR2.
Immunogen
A synthetic peptide corresponding to amino acids 200-300 of human EGR2.
Host
Rabbit
Reactivity
Human, Pig
Specificity
This antibody is specific to EGR2.
Form
Liquid
Recommend Usage
Western Blot (2 ug/mL)
The optimal working dilution should be determined by the end user.Storage Buffer
In Tris-glycine, 150 mM NaCl (0.09% sodium azide)
Storage Instruction
Store at 4°C for short term. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Tissue lysate)
Western blot analysis of EGR2 in human fetal lung tissue using EGR2 polyclonal antibody (Cat # PAB12439). -
Gene Info — EGR2
Entrez GeneID
1959Protein Accession#
P11161Gene Name
EGR2
Gene Alias
AT591, CMT1D, CMT4E, DKFZp686J1957, FLJ14547, KROX20
Gene Description
early growth response 2 (Krox-20 homolog, Drosophila)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq
Other Designations
KROX-20, Drosophila, homolog (early growth response-2)|Krox-20 homolog|OTTHUMP00000062133|early growth response 2 protein
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Interactome
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Disease
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Publication Reference
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Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells.
Harris JE, Bishop KD, Phillips NE, Mordes JP, Greiner DL, Rossini AA, Czech MP.
The Journal of Immunology 2004 Dec; 173(12):7331.
Application:WB-Ce, WB-Tr, Mouse, A.E7 T cells.
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A molecular dissection of the carboxyterminal tails of the major neurofilament subunits NF-M and NF-H.
Harris J, Ayyub C, Shaw G.
Journal of Neuroscience Research 1991 Sep; 30(1):47.
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Early growth response gene-2, a zinc-finger transcription factor, is required for full induction of clonal anergy in CD4+ T cells.
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