FOS polyclonal antibody
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Specification
Product Description
Sheep polyclonal antibody raised against synthetic peptide of FOS.
Immunogen
A synthetic peptide (conjugated diphtheria toxoid) corresponding to amino acids 2-17 of human FOS.
Sequence
MFSGFNADYEASSSRC
Host
Sheep
Reactivity
Hamster, Human, Rabbit, Rat
Specificity
This antiserum shows a high level of specificity for cFOS confirmed by immunohostochemistry.
Form
Lyophilized
Recommend Usage
Immunohistochemistry (1:500-1:8000)
Western Blot (1:500-1:8000)
The optimal dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with 100 uL of deionized water, store at -20°C or lower.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot
Immunohistochemistry (Frozen sections)
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Gene Info — FOS
Entrez GeneID
2353Protein Accession#
P01100;Q4FDN1;P01101;Q56TL8;Q5XQC6Gene Name
FOS
Gene Alias
AP-1, C-FOS
Gene Description
v-fos FBJ murine osteosarcoma viral oncogene homolog
Omim ID
164810Gene Ontology
HyperlinkGene Summary
The Fos gene family consists of 4 members: FOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP-1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. In some cases, expression of the FOS gene has also been associated with apoptotic cell death. [provided by RefSeq
Other Designations
FBJ murine osteosarcoma viral (v-fos) oncogene homolog (oncogene FOS)|activator protein 1|cellular oncogene c-fos
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