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Last updated: 2015/11/22
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BDNF polyclonal antibody

  • Catalog # : PAB0745
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against synthetic peptide of BDNF.
  • Immunogen:
  • A synthetic peptide (conjugated with KLH) corresponding to amino acids 69-82 of human BDNF.
  • Sequence:
  • Host:
  • Rabbit
  • Theoretical MW (kDa):
  • 35
  • Reactivity:
  • Human, Mouse, Rat
  • Specificity:
  • Used in western blot, this antiserum detects a 35 KDa band corresponding to the molecular weight of proBDNF. No cross reactivity with other proneurotrophins was detected.
  • Form:
  • Lyophilized
  • Recommend Usage:
  • Immunohistochemistry (1-5 ug/mL)
    Western Blot (1-5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • Lyophilized from PBS
  • Storage Instruction:
  • Store at 4°C on dry atmosphere.
    After reconstitution with deionized water, store at -20°C or lower.
    Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot
  • Immunohistochemistry
  • Immunohistochemistry
  • Pro - BDNF staining within the rat spinal cord dorsal horn. Normal cryostat sections of adult rat cord were stained with recombinant human anti - proBDNF (Cat # PAB0745) and detected with HRP labelled anti - rabbit antibody. Dilution 1 : 2000 in Human mouse and rat. (Image courtesy of Dr Xin-fu Zhou).
  • Application Image
  • Western Blot
  • Gene Information
  • Entrez GeneID:
  • 627
  • Gene Name:
  • BDNF
  • Gene Alias:
  • MGC34632
  • Gene Description:
  • brain-derived neurotrophic factor
  • Gene Summary:
  • The protein encoded by this gene is a member of the nerve growth factor family. It is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of this gene is reduced in both Alzheimer's and Huntington disease patients. This gene may play a role in the regulation of stress response and in the biology of mood disorders. Multiple transcript variants encoding distinct isoforms have been described for this gene. [provided by RefSeq
  • Other Designations:
  • neurotrophin
  • Related Disease
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