APEX2 polyclonal antibody
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More Files
- More Functions
Western Blot (Cell lysate)
Western blot analysis of APEXL2 in HeLa cell lysates using APEX2 polyclonal antibody (Cat # PAB0203) at a dilution of 1 : 500.
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Specification
Product Description
Rabbit polyclonal antibody raised against synthetic peptide of APEX2.
Immunogen
A synthetic peptide corresponding to human APEXL2.
Host
Rabbit
Reactivity
Human
Form
Liquid
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In PBS (0.02% sodium azide)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Western Blot (Cell lysate)
Western blot analysis of APEXL2 in HeLa cell lysates using APEX2 polyclonal antibody (Cat # PAB0203) at a dilution of 1 : 500. -
Gene Info — APEX2
Entrez GeneID
27301Gene Name
APEX2
Gene Alias
APE2, APEXL2, XTH2
Gene Description
APEX nuclease (apurinic/apyrimidinic endonuclease) 2
Gene Ontology
HyperlinkGene Summary
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes a protein shown to have a weak class II AP endonuclease activity. Most of the encoded protein is located in the nucleus but some is also present in mitochondria. This protein may play an important role in both nuclear and mitochondrial base excision repair (BER). [provided by RefSeq
Other Designations
APEX nuclease-like 2|OTTHUMP00000023390|OTTHUMP00000061908|apurinic/apyrimidinic endonuclease 2|apurinic/apyrimidinic endonuclease-like 2
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Interactome
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Pathway
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Disease
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