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BIOtech
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RCAN1 (C-term) Peptide

  • Catalog # : P1946
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  • Specification
  • Product Description:
  • This synthetic peptide sequence is selected from human RCAN1 construct and is used as the immunogen for PAB4386.
  • Sequence:
  • C terminus of Human RCAN1
  • Form:
  • Lyophilized with 100% acetonitrile
  • Storage Buffer:
  • Reconstitute with 100 uL deionized water for a final concentration of 1 mg/mL.
  • Storage Instruction:
  • Store at 4°C. For long term storage store at-20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product is for research use only. Not for use in diagnostics or therapeutics.
  • Applications
  • Blocking
  • Application Image
  • Blocking
  • Gene Information
  • Entrez GeneID:
  • 1827
  • Protein Accession#:
  • NP_004405;Q7Z555
  • Gene Name:
  • RCAN1
  • Gene Alias:
  • ADAPT78,CSP1,DSC1,DSCR1,MCIP1,RCN1
  • Gene Description:
  • regulator of calcineurin 1
  • Gene Summary:
  • The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • Down syndrome candidate region 1,Down syndrome critical region gene 1,calcipressin 1,calcium and oxidant-inducible mRNA,modulatory calcineurin-interacting protein 1,myocyte-enriched calcineurin-interacting protein 1,near DSCR proline-rich protein
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