IL18 monoclonal antibody, clone 2
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More Files
- More Functions
Western Blot (Recombinant protein)
Western blot analysis of recombinant IL18 protein with IL18 monoclonal antibody, clone 2 (Cat # MAB9935) at 1:1000 dilution.
Immunohistochemistry
Immunohistochemical staining of human liver cancer tissue section with IL18 monoclonal antibody, clone 2 (Cat # MAB9935) at 1:10 dilution.
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Specification
Product Description
Mouse monoclonal antibody raised against full length recombinant IL18.
Immunogen
Recombinant protein corresponding to full length human IL18.
Host
Mouse
Reactivity
Human
Form
Liquid
Purification
Affinity purification
Isotype
IgG2b
Recommend Usage
Western blot (1:1000)
Immunohistochemistry (1:10)
The optimal working dilution should be determined by the end user.Storage Buffer
In Citrate-Tris-HCl buffer, pH 7.0 (0.02% Proclin 300)
Storage Instruction
Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing. -
Applications
Western Blot (Cell lysate)
Western Blot (Recombinant protein)
Western blot analysis of recombinant IL18 protein with IL18 monoclonal antibody, clone 2 (Cat # MAB9935) at 1:1000 dilution.Immunohistochemistry
Immunohistochemical staining of human liver cancer tissue section with IL18 monoclonal antibody, clone 2 (Cat # MAB9935) at 1:10 dilution.Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL18
Entrez GeneID
3606GeneBank Accession#
NM_001562.2Protein Accession#
NP_001553.1Gene Name
IL18
Gene Alias
IGIF, IL-18, IL-1g, IL1F4, MGC12320
Gene Description
interleukin 18 (interferon-gamma-inducing factor)
Omim ID
600953Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. [provided by RefSeq
Other Designations
IL-1 gamma|interferon-gamma-inducing factor|interleukin 18|interleukin-1 gamma|interleukin-18
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Interactome
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Pathway
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Disease
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