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Last updated: 2014/4/21
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BIOtech
BULK-new

ITGAM monoclonal antibody, clone ICRF44 (PE)

  • Catalog # : MAB6032
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native ITGAM.
  • Immunogen:
  • Native purified ITGAM from rheumatoid synovial cells and human monocytes.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • Specificity human CD11b/Mac-1alpha
  • Form:
  • Liquid
  • Conjugation:
  • PE
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (10 ul/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.1 mg/mL sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Do not freeze.
    Avoid prolonged exposure to light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry (Frozen sections)
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry (Frozen sections)
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 3684
  • Gene Name:
  • ITGAM
  • Gene Alias:
  • CD11B,CR3A,MAC-1,MAC1A,MGC117044,MO1A,SLEB6
  • Gene Description:
  • integrin, alpha M (complement component 3 receptor 3 subunit)
  • Gene Summary:
  • This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • antigen CD11b (p170),complement component receptor 3, alpha,integrin alpha M,macrophage antigen alpha polypeptide,neutrophil adherence receptor alpha-M subunit
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