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Last updated: 2014/4/14
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BIOtech
BULK-new

BCAM monoclonal antibody, clone BRIC221

  • Catalog # : MAB5244
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native BCAM.
  • Immunogen:
  • Native purified BCAM from human erythrocytes.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes a non-polymorphic determinant on both the 85 and 78kD Lutheran (Lu) glycoproteins. BRIC 221 specifically recognizes an epitope in the fourth extracellular domain of Lu glycoprotein. CD239 is expressed by erythrocytes in the peripheral blood.
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Recommend Usage:
  • Flow Cytometry (10ul of the suggested working dilution to label 106 cells or 100ul)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS, pH 7.5 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Flow Cytometry
  • Application Image
  • Western Blot
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 4059
  • Gene Name:
  • BCAM
  • Gene Alias:
  • AU,CD239,LU,MSK19
  • Gene Description:
  • basal cell adhesion molecule (Lutheran blood group)
  • Gene Summary:
  • Lutheran blood group glycoprotein is a member of the immunoglobulin superfamily and a receptor for the extracellular matrix protein, laminin. The protein contains five, N-terminus, extracellular immunoglobulin domains, a single transmembrane domain, and a short, C-terminal cytoplasmic tail. This protein may play a role in epithelial cell cancer and in vaso-occlusion of red blood cells in sickle cell disease. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
  • Other Designations:
  • Auberger b antigen,B-CAM cell surface glycoprotein,B-cell adhesion molecule,F8/G253 antigen,Lutheran blood group (Auberger b antigen included),antigen identified by monoclonal antibody F8,basal cell adhesion molecule,basal cell adhesion molecule (Lu and A
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