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Last updated: 2015/3/1
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TNFRSF10A monoclonal antibody, clone DR-4-02 (FITC)

  • Catalog # : MAB5076
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant TNFRSF10A.
  • Immunogen:
  • Recombinant Fc fusion protein corresponding to extracellular region of TNFRSF10A.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • This antibody recognizes TRAIL-R1 (DR4), a human death receptor 4 (468 amino acids) expressed in most human tissues (spleen, peripheral blood leucocytes, thymus) and in a variety of tumour-derived.
  • Form:
  • Liquid
  • Conjugation:
  • FITC
  • Concentration:
  • 0.1 mg/mL
  • Isotype:
  • IgG1
  • Recommend Usage:
  • Flow Cytometry (5 ug/mL)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.2% BSA, 15 mM sodium azide)
  • Storage Instruction:
  • Store in the dark at 4°C. Do not freeze.
    Avoid prolonged exposure to light.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Flow Cytometry
  • Application Image
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 8797
  • Gene Name:
  • TNFRSF10A
  • Gene Alias:
  • APO2,CD261,DR4,MGC9365,TRAILR-1,TRAILR1
  • Gene Description:
  • tumor necrosis factor receptor superfamily, member 10a
  • Gene Summary:
  • The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is activated by tumor necrosis factor-related apoptosis inducing ligand (TNFSF10/TRAIL), and thus transduces cell death signal and induces cell apoptosis. Studies with FADD-deficient mice suggested that FADD, a death domain containing adaptor protein, is required for the apoptosis mediated by this protein. [provided by RefSeq
  • Other Designations:
  • TNF-related apoptosis inducing ligand receptor 1,cytotoxic TRAIL receptor,death receptor 4
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