B2M monoclonal antibody, clone B2M-01 (FITC)
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Specification
Product Description
Mouse monoclonal antibody raised against B2M.
Immunogen
Purified human B2M.
Host
Mouse
Reactivity
Human
Specificity
This antibody reacts with beta2-microglobulin (B2M) associated with cell-surface MHC Class I molecules and other membrane antigens as well as with soluble beta2-microglobulin.
Form
Liquid
Conjugation
FITC
Concentration
1 mg/mL
Isotype
IgG2a
Recommend Usage
Flow Cytometry (1:200)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store in the dark at 4°C. Do not freeze.
Avoid prolonged exposure to light.
Aliquot to avoid repeated freezing and thawing.Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — B2M
Entrez GeneID
567Gene Name
B2M
Gene Alias
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Gene Description
beta-2-microglobulin
Gene Ontology
HyperlinkGene Summary
This gene encodes a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells. The protein has a predominantly beta-pleated sheet structure that can form amyloid fibrils in some pathological conditions. A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia
Other Designations
beta chain of MHC class I molecules|beta-2-microglobin
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Interactome
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Pathway
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Disease
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Publication Reference
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Urine proteomic profiling of pediatric nephrotic syndrome.
Khurana M, Traum AZ, Aivado M, Wells MP, Guerrero M, Grall F, Libermann TA, Schachter AD.
Pediatric Nephrology (Berlin, Germany) 2006 Sep; 21(9):1257.
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The use of murine monoclonal antibody B2M-01 for detection and purification of human beta 2-microglobulin.
Hilgert I, Horejsi V, Kristofova H.
Folia Biol (Praha) 1984 Jan; 30(6):369.
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Urine proteomic profiling of pediatric nephrotic syndrome.
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