Mouse monoclonal antibody raised against synthetic peptide of CD38.
A synthetic peptide corresponding to human CD38.
The monoclonal antibody is directed against the CD38-antigen, which is strongly expressed plasma cell. The CD 38-antigen is expressed at variable levels on the majority of hemopoietic cells, prevalently during early differentiation and activation. Reacts with the 45 KDa type II single chain transmembrana glycoprotein, the cellular function is positive and negative regulator of cell activation and proliferation, depending on the cellular environment and it is involved in adhesion between human lymphocytes and endothelial cells. Disease relevance of CD38: Leukemia phenotyping and classification. Monitoring of HIV-1 infection and progression. Targeting of immunotoxin antibody in the treatment of myeloma.
Flow Cytometry (20 ul/106 cells) The optimal working dilution should be determined by the end user.
In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
Store in the dark at 4°C. Avoid prolonged exposure to light.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
CD38 is a novel multifunctional ectoenzyme widely expressed in cells and tissues especially in leukocytes. CD38 also functions in cell adhesion,signal transduction and calcium signaling. [provided by RefSeq