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Last updated: 2014/4/14
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BIOtech
BULK-new

CD4 monoclonal antibody, clone HP2/6

  • Catalog # : MAB4960
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native CD4.
  • Immunogen:
  • Native purified CD4 from rabbit thymocytes.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Specificity:
  • The monoclonal antibody is directed against the CD4-antigen (T4-antigen), which is expressed on human peripheral T lymphocytes and 80% of thymocytes. The monoclonal antibody reacts on a low level with human monocytes and macrophages. The monoclonal antibody does not react with B-cells, granulocytes and thrombocytes. 60Kd MW lymphocyte surface antigen identified by monoclonal antibodies belonging to the CD4 cluster and present on 54% of peripheral blood T lymphocytes, 50% of thymocytes and some malignant cells of T cell origin. Normal B lymphocytes, monocytes or granulocytes do not express surface CD4 antigen although cytoplasmic expression has been observed in monocytes/macrophages. The CD4 positive T lymphocyte subpopulation has been characterised functionally as comprising helper cells active in amplification of immune responses.
  • Form:
  • Liquid
  • Isotype:
  • IgG2a
  • Recommend Usage:
  • Flow Cytometry (20 ul/106 cells)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In buffer containing 1% BSA, pH 7.2 (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Immunohistochemistry
  • Immunofluorescence
  • Flow Cytometry
  • Application Image
  • Immunohistochemistry
  • Immunofluorescence
  • Flow Cytometry
  • Gene Information
  • Entrez GeneID:
  • 920
  • Gene Name:
  • CD4
  • Gene Alias:
  • CD4mut
  • Gene Description:
  • CD4 molecule
  • Other Designations:
  • CD4 antigen,CD4 antigen (p55),CD4 receptor
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