CD48 monoclonal antibody, clone MEM-102 (Biotin)
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Specification
Product Description
Mouse monoclonal antibody raised against native CD48.
Immunogen
Native purified CD48 from Raji Burkitt's lymphoma cell line.
Host
Mouse
Theoretical MW (kDa)
40-47
Reactivity
Human, Non-Human Primates
Specificity
This antibody reacts with CD48 antigen (Blast-1), a 40-47 KDa GPI-anchored membrane protein (immunoglobulin supergene family) widely expressed on hematopoietic cells; it is negative on granulocytes, platelets and erythrocytes.
Form
Liquid
Conjugation
Biotin
Concentration
1 mg/mL
Isotype
IgG1
Recommend Usage
Flow Cytometry (1:1000)
The optimal working dilution should be determined by the end user.Storage Buffer
In PBS, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Flow Cytometry
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Gene Info — CD48
Entrez GeneID
962Gene Name
CD48
Gene Alias
BCM1, BLAST, BLAST1, MEM-102, SLAMF2, hCD48, mCD48
Gene Description
CD48 molecule
Omim ID
109530Gene Ontology
HyperlinkGene Summary
BLAST1 is the designation used for an activation-associated cell surface glycoprotein of 40 to 45 kD expressed primarily in mitogen-stimulated human lymphocytes. The protein sequence predicted by the cDNA encoding BLAST1 indicates that BLAST1 is a member of the immunoglobulin supergene family. Yokoyama (1991) identified the BLAST1 activation/adhesion molecule as CD48.[supplied by OMIM
Other Designations
CD48 antigen (B-cell membrane protein)|OTTHUMP00000025680|OTTHUMP00000060268
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Interactome
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Publication Reference
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CD48 is an allergen and IL-3-induced activation molecule on eosinophils.
Munitz A, Bachelet I, Eliashar R, Khodoun M, Finkelman FD, Rothenberg ME, Levi-Schaffer F.
Journal of Immunology 2006 Jul; 177(1):77.
Application:Flow Cyt, Human, Mouse, Human nasal polyp eosinophils, Peripheral blood eosinophils, Mouse bronchoalveolar lavage fluid.
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The human leucocyte antigen CD48 (MEM-102) is closely related to the activation marker Blast-1.
Korínek V, Stefanová I, Angelisová P, Hilgert I, Horejsí V.
Immunogenetics 1991 Jan; 33(2):108.
Application:WB-Ce, WB-Tr, Human, Monkey, COS, PBMCs, Raji cells.
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Monoclonal antibodies against human leucocyte antigens. III. Antibodies against CD45R, CD6, CD44 and two newly described broadly expressed glycoproteins MEM-53 and MEM-102.
Bazil V, Stefanová I, Hilgert I, Kristofová H, Vanĕk S, Bukovský A, Horejsí V.
Folia Biol (Praha) 1989 Jan; 35(5):289.
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CD48 is an allergen and IL-3-induced activation molecule on eosinophils.
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