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BIOtech
BULK-new

CAV1 monoclonal antibody, clone 4D6

  • Catalog # : MAB3768
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant CAV1.
  • Immunogen:
  • Recombinant protein corresponding to N-terminus of human CAV1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG2a, kappa
  • Recommend Usage:
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
    Western Blot (1:4000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In tissue culture supernatant (15 mM sodium azide)
  • Storage Instruction:
  • Store at 4°C.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Application Image
  • Western Blot
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Gene Information
  • Entrez GeneID:
  • 857
  • Gene Name:
  • CAV1
  • Gene Alias:
  • BSCL3,CAV,CGL3,MSTP085,VIP21
  • Gene Description:
  • caveolin 1, caveolae protein, 22kDa
  • Gene Summary:
  • The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene. [provided by RefSeq
  • Other Designations:
  • OTTHUMP00000025031,caveolae protein, 22-kD,caveolin 1,caveolin 1 caveolae protein, 22kD,caveolin 1, alpha isoform,caveolin 1, beta isoform,caveolin-1 beta isoform protein,cell growth-inhibiting protein 32
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