HT-29 cell lysate was used with EGFR monoclonal antibody, clone SB41a (Cat # MAB3323) , 1st lane, and Mouse Anti-EGFR-HRP, 2 nd lane. Goat Anti-Mouse IgG2a was used in conjunction with the unlabeled antibody.
The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. [provided by RefSeq
avian erythroblastic leukemia viral (v-erb-b) oncogene homolog,cell growth inhibiting protein 40,cell proliferation-inducing protein 61,epidermal growth factor receptor