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Last updated: 2015/11/29
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HNRNPA1 monoclonal antibody, clone 9H10

  • Catalog # : MAB2492
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against native HNRNPA1.
  • Immunogen:
  • Native purified human HNRNPA1.
  • Host:
  • Mouse
  • Theoretical MW (kDa):
  • 34
  • Reactivity:
  • Human
  • Specificity:
  • Detects a band of approximately 34 KDa.
  • Form:
  • Liquid
  • Isotype:
  • IgG2b
  • Quality Control Testing:
  • Antibody Reactive Against Native Purified Protein.
  • Recommend Usage:
  • Western Blot (1:2000-1:4000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.09% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Publication Reference
  • Applications
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • Western blot of HNRNPA1 monoclonal antibody, clone 9H10 (Cat # MAB2492) on HeLa cell extract.
  • Immunofluorescence
  • Immunoprecipitation
  • Application Image
  • Western Blot (Cell lysate)
  • Western Blot (Cell lysate)
  • enlarge
  • Immunofluorescence
  • Immunoprecipitation
  • Gene Information
  • Entrez GeneID:
  • 3178
  • Gene Name:
  • Gene Alias:
  • HNRPA1,MGC102835
  • Gene Description:
  • heterogeneous nuclear ribonucleoprotein A1
  • Gene Summary:
  • This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has two repeats of quasi-RRM domains that bind to RNAs. It is one of the most abundant core proteins of hnRNP complexes and it is localized to the nucleoplasm. This protein, along with other hnRNP proteins, is exported from the nucleus, probably bound to mRNA, and is immediately re-imported. Its M9 domain acts as both a nuclear localization and nuclear export signal. The encoded protein is involved in the packaging of pre-mRNA into hnRNP particles, transport of poly A+ mRNA from the nucleus to the cytoplasm, and may modulate splice site selection. It is also thought have a primary role in the formation of specific myometrial protein species in parturition. Multiple alternatively spliced transcript variants have been found for this gene but only two transcripts are fully described. These variants have multiple alternative transcription initiation sites and multiple polyA sites. [provided by RefSeq
  • Other Designations:
  • helix-destabilizing protein,heterogeneous nuclear ribonucleoprotein A1B protein,heterogeneous nuclear ribonucleoprotein B2 protein,heterogeneous nuclear ribonucleoprotein core protein A1,nuclear ribonucleoprotein particle A1 protein,single-strand DNA-bind
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