Mouse monoclonal antibody raised against full length recombinant HNRNPM.
Recombinant protein corresponding to full length human HNRNPM.
Bovine, Human, Mouse, Pig, Rabbit, Rat
This antibody is specific to human RNP M3-M4.
Quality Control Testing:
Antibody Reactive Against Recombinant Protein.
Immunocytochemistry (1:1000) Immunofluorescence (1:1000) Immunohistochemistry (Frozen sections) (1:1000) Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (1:1000) Immunoprecipitation (1:1000) Western Blot (1:1000) The optimal working dilution should be determined by the end user.
In buffer containing 0.1% sodium azide
Store at -20°C or -80°C. Aliquot to avoid repeated freezing and thawing.
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Multiple alternatively spliced transcript variants are known for this gene but only two transcripts has been isolated. [provided by RefSeq