KLK3 monoclonal antibody
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Specification
Product Description
Mouse monoclonal antibody raised against native KLK3.
Immunogen
Native purified human KLK3.
Host
Mouse
Reactivity
Human
Specificity
This antibody is specific to KLK3. No cross-reactivity with human albumin, AFP, CEA, PAP, CA 125, CA 15-3, or CA 19-9.
Form
Liquid
Isotype
IgG2a
Quality Control Testing
Antibody Reactive Against Native Purified Protein.
Recommend Usage
The optimal working dilution should be determined by the end user.
Storage Buffer
In 15 mM KPO4 buffer, 0.85% NaCl, pH 7.4 (0.09% sodium azide)
Storage Instruction
Store at 4°C.
Note
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Applications
Immunohistochemistry
Sandwich ELISA
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Gene Info — KLK3
Entrez GeneID
354Gene Name
KLK3
Gene Alias
APS, KLK2A1, PSA, hK3
Gene Description
kallikrein-related peptidase 3
Omim ID
176820Gene Ontology
HyperlinkGene Summary
Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
P-30 antigen|gamma-seminoprotein|kallikrein 3, (prostate specific antigen)|prostate specific antigen|semenogelase|seminin
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Interactome
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Pathway
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Disease
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