IL18 monoclonal antibody, clone mxsghk-18
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Specification
Product Description
Mouse monoclonal antibody raised against recombinant IL18.
Immunogen
Recombinant protein corresponding to human IL18.
Host
Mouse
Reactivity
Human
Form
Lyophilized
Purification
Protein A purification
Isotype
IgG1
Recommend Usage
ELISA (1:10000)
The optimal working dilution should be determined by the end user.Storage Buffer
Lyophilized from PBS.
Storage Instruction
Store at 4°C on dry atmosphere.
After reconstitution with deionized water, store at -20°C. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.
Aliquot to avoid repeated freezing and thawing. -
Applications
Enzyme-linked Immunoabsorbent Assay
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Gene Info — IL18
Entrez GeneID
3606Gene Name
IL18
Gene Alias
IGIF, IL-18, IL-1g, IL1F4, MGC12320
Gene Description
interleukin 18 (interferon-gamma-inducing factor)
Omim ID
600953Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. [provided by RefSeq
Other Designations
IL-1 gamma|interferon-gamma-inducing factor|interleukin 18|interleukin-1 gamma|interleukin-18
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Interactome
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Pathway
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Disease
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