Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) with KRT7 monoclonal antibody, clone SP52 (Cat # MAB11033). (A) human breast carcinoma, (B) human breast, (C) human pancreatic adenocarcinoma, (D) human breast ductal cell carcinoma, (E) human bladder, (F) human bladder transitional cell carcinoma, (G) human prostate, (H) human prostate adenocarcinoma, (I) human endometrium, (J) human endometrial adenocarcinoma, (K) human pancreas
Flow cytometric analysis of HeLa cells (green) with KRT7 monoclonal antibody, clone SP52 (Cat # MAB11033) at 1:100 dilution, compare to negative control of rabbit IgG (blue).
The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels. The genes encoding the type II cytokeratins are clustered in a region of chromosome 12q12-q13. Alternative splicing may result in several transcript variants; however, not all variants have been fully described. [provided by RefSeq
cytokeratin 7,keratin, 55K type II cytoskeletal,keratin, simple epithelial type I, K7,keratin, type II cytoskeletal 7,sarcolectin,type II mesothelial keratin K7