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CYP1A1 monoclonal antibody, clone 6G5

  • Catalog # : MAB10576
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  • Specification
  • Product Description:
  • Mouse monoclonal antibody raised against partial recombinant CYP1A1.
  • Immunogen:
  • Recombinant protein corresponding to human CYP1A1.
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Form:
  • Liquid
  • Isotype:
  • IgG1
  • Recommend Usage:
  • ELISA (1:10000)
    Western Blot (1:500-1:2000)
    Immunohistochemistry (1:200-1:1000)
    The optimal working dilution should be determined by the end user.
  • Storage Buffer:
  • In PBS (0.5% protein stabilizer, 0.05% sodium azide)
  • Storage Instruction:
  • Store at 4°C. For long term storage store at -20°C.
    Aliquot to avoid repeated freezing and thawing.
  • Note:
  • This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
  • Applications
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • Western blot analysis using CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB10576) against human CYP1A1 (aa : 203-461) recombinant protein. (Expected MW is 60 kDa)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemical analysis of paraffin-embedded human ovarian cancer (A) and human rectum cancer (B) tissues using CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB10576) with DAB staining.
  • ELISA
  • ELISA
  • ELISA detection with CYP1A1 monoclonal antibody, clone 6G5 (Cat # MAB10576).
  • Application Image
  • Western Blot (Recombinant protein)
  • Western Blot (Recombinant protein)
  • enlarge
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
  • enlarge
  • Gene Information
  • Entrez GeneID:
  • 1543
  • Gene Name:
  • CYP1A1
  • Gene Alias:
  • AHH,AHRR,CP11,CYP1,P1-450,P450-C,P450DX
  • Gene Description:
  • cytochrome P450, family 1, subfamily A, polypeptide 1
  • Gene Summary:
  • This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. [provided by RefSeq
  • Other Designations:
  • aryl hydrocarbon hydroxylase,cytochrome P1-450, dioxin-inducible,cytochrome P450 1A1,cytochrome P450, subfamily I (aromatic compound-inducible), polypeptide 1,flavoprotein-linked monooxygenase,xenobiotic monooxygenase
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