AGE-AGER in vitro Binding Assay Kit
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More Files
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Result Data
Result Data
Typical dose dependent curve of Recombinant His-tagged AGER
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Specification
Product Description
AGE-AGER in vitro Binding Assay Kit is primarily designed to screening inhibitors of AGE2 (glyceraldehyde-modified AGE)-sRAGE interaction (soluble AGER) in vitro.
Label
HRP-conjugated
Detection Method
Colorimetric
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store the kit at 4°C.
Note
Result Data
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Applications
Functional Study
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Gene Info — AGER
Entrez GeneID
177Gene Name
AGER
Gene Alias
MGC22357, RAGE
Gene Description
advanced glycosylation end product-specific receptor
Omim ID
600214Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the immunoglobulin superfamily of cell surface molecules. It is a receptor for various molecules, including the amyloidogenic form of serum amyloid A, amyloid-beta protein, members of the S100/calgranulin superfamily and advanced glycation end products. The gene lies within the major histocompatibility complex (MHC) class III region on chromosome 6. Alternative splicing results in two transcript variants encoding different isoforms. [provided by RefSeq
Other Designations
OTTHUMP00000029155|OTTHUMP00000029156|advanced glycosylation end product-specific receptor RAGE3|advanced glycosylation end product-specific receptor variant sRAGE1|advanced glycosylation end product-specific receptor variant sRAGE2|receptor for advanced
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Interactome
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Disease
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