SERPINC1 (Human) ELISA Kit
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Specification
Product Description
SERPINC1 (Human) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of human SERPINC1.
Suitable Sample
Cell Culture Samples, Milk, Saliva, Urine, CSF
Sample Volume
50 uL
Label
Peroxidase-conjugated
Detection Method
Colorimetric
Assay Type
Quantitative
Calibration Range
3.125 to 200 ng/mL
Reactivity
Human
Regulation Status
For research use only (RUO)
Storage Instruction
Store components of the kit at 4°C or -20°C as described in the protocol.
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Applications
Quantification
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Gene Info — SERPINC1
Entrez GeneID
462Gene Name
SERPINC1
Gene Alias
AT3, ATIII, MGC22579
Gene Description
serpin peptidase inhibitor, clade C (antithrombin), member 1
Omim ID
107300Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a plasma protease inhibitor and a member of the serpin superfamily. This protein inhibits thrombin as well as other activated serine proteases of the coagulation system, and it regulates the blood coagulation cascade. The protein includes two functional domains: the heparin binding-domain at the N-terminus of the mature protein, and the reactive site domain at the C-terminus. The inhibitory activity is enhanced by the presence of heparin. More than 120 mutations have been identified for this gene, many of which are known to cause antithrombin-III deficiency. [provided by RefSeq
Other Designations
OTTHUMP00000035393|antithrombin (aa 375-432)|antithrombin III|coding sequence signal peptide antithrombin part 1|serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1|signal peptide antithrombin part 1
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Interactome
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Pathway
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Disease
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Publication Reference
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Coagulation and fibrinolysis parameters in type 2 diabetic patients with and without diabetic vascular complications.
Erem C, Hacihasanoglu A, Celik S, Ovali E, Ersoz HO, Ukinc K, Deger O, Telatar M.
Medical Principles and Practice 2005 Jan; 14(1):22.
Application:Quant, Human, Blood from type 2 diabetic patients.
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Antithrombin III inhibits nuclear factor kappaB activation in human monocytes and vascular endothelial cells.
Oelschlager C, Romisch J, Staubitz A, Stauss H, Leithauser B, Tillmanns H, Holschermann H.
Blood 2002 Jun; 99(11):4015.
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[Are there certified indications for the use of antithrombin III in intensive care].
Kulka PJ, Tryba M, Lange S.
Anasthesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2001 Mar; 36(3):143.
Application:Quant, Human, Serum, Plasma.
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Coagulation and fibrinolysis parameters in type 2 diabetic patients with and without diabetic vascular complications.
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