TNFRSF13C 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
TNFRSF13C transfected lysate.
Western Blot
Lane 1: TNFRSF13C transfected lysate ( 20.35 KDa)
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFRSF13C full-length
Host
Human
Theoretical MW (kDa)
20.35
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFRSF13C antibody (H00115650-B01) by Western Blots.
SDS-PAGE Gel
TNFRSF13C transfected lysate.
Western Blot
Lane 1: TNFRSF13C transfected lysate ( 20.35 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TNFRSF13C
Entrez GeneID
115650GeneBank Accession#
NM_052945.2Protein Accession#
NP_443177.1Gene Name
TNFRSF13C
Gene Alias
BAFF-R, BAFFR, CD268, MGC138235
Gene Description
tumor necrosis factor receptor superfamily, member 13C
Omim ID
606269Gene Ontology
HyperlinkGene Summary
B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival. [provided by RefSeq
Other Designations
B cell-activating factor receptor|BAFF receptor|OTTHUMP00000028746
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Pathway
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Disease
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