POLR1B polyclonal antibody (A01)
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant POLR1B.
Immunogen
POLR1B (NP_061887, 963 a.a. ~ 1072 a.a) partial recombinant protein with GST tag.
Sequence
GEMLKAAGYNFYGTERLYSGISGLELEADIFIGVVYYQRLRHMVSDKFQVRTTGARDRVTNQPIGGRNVQGGIRFGEMERDALLAHGTSFLLHDRLFNCSDRSVAHVCVK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (90); Rat (87)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (38.21 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — POLR1B
Entrez GeneID
84172GeneBank Accession#
NM_019014Protein Accession#
NP_061887Gene Name
POLR1B
Gene Alias
FLJ10816, FLJ21921, MGC131780, RPA135, RPA2, Rpo1-2
Gene Description
polymerase (RNA) I polypeptide B, 128kDa
Omim ID
602000Gene Ontology
HyperlinkGene Summary
Eukaryotic RNA polymerase I (pol I) is responsible for the transcription of ribosomal RNA (rRNA) genes and production of rRNA, the primary component of ribosomes. Pol I is a multisubunit enzyme composed of 6 to 14 polypeptides, depending on the species. Most of the mass of the pol I complex derives from the 2 largest subunits, Rpa1 and Rpa2 in yeast. POLR1B is homologous to Rpa2 (Seither and Grummt, 1996 [PubMed 8921381]).[supplied by OMIM
Other Designations
DNA-directed RNA polymerase I 135kDa polypeptide|RNA polymerase I polypeptide B|RNA polymerase I subunit 2
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