BIRC7 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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SDS-PAGE Gel
BIRC7 transfected lysate
Western Blot
Lane 1: BIRC7 transfected lysate ( 32.89 KDa).
Lane 2: Non-transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-BIRC7 full-length
Host
Human
Theoretical MW (kDa)
32.89
Interspecies Antigen Sequence
Mouse (64)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-BIRC7 antibody (H00079444-B01) by Western Blots.
SDS-PAGE Gel
BIRC7 transfected lysate
Western Blot
Lane 1: BIRC7 transfected lysate ( 32.89 KDa).
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — BIRC7
Entrez GeneID
79444GeneBank Accession#
BC014475Protein Accession#
AAH14475Gene Name
BIRC7
Gene Alias
KIAP, LIVIN, ML-IAP, MLIAP, RNF50
Gene Description
baculoviral IAP repeat-containing 7
Omim ID
605737Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq
Other Designations
OTTHUMP00000031536|OTTHUMP00000031537|baculoviral IAP repeat-containing protein 7|kidney inhibitor of apoptosis protein|livin inhibitor of apoptosis|livin inhibitor-of-apoptosis|melanoma inhibitor of apoptosis protein
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