BIRC7 purified MaxPab mouse polyclonal antibody (B02P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of BIRC7 expression in transfected 293T cell line (H00079444-T02) by BIRC7 MaxPab polyclonal antibody.
Lane 1: BIRC7 transfected lysate(32.78 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human BIRC7 protein.
Immunogen
BIRC7 (NP_647478.1, 1 a.a. ~ 298 a.a) full-length human protein.
Sequence
MGPKDSAKCLHRGPQPSHWAAGDGPTQERCGPRSLGSPVLGLDTCRAWDHVDGQILGQLRPLTEEEEEEGAGATLSRGPAFPGMGSEELRLASFYDWPLTAEVPPELLAAAGFFHTGHQDKVRCFFCYGGLQSWKRGDDPWTEHAKWFPSCQFLLRSKGRDFVHSVQETHSQLLGSWDPWEEPEDAAPVAPSVPASGYPELPTPRREVQSESAQEPGGVSPAEAQRAWWVLEPPGARDVEAQLRRLQEERTCKVCLDRAVSIVFVPCGHLVCAECAPGLQLCPICRAPVRSRVRTFLS
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (64)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of BIRC7 expression in transfected 293T cell line (H00079444-T02) by BIRC7 MaxPab polyclonal antibody.
Lane 1: BIRC7 transfected lysate(32.78 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — BIRC7
Entrez GeneID
79444GeneBank Accession#
NM_139317Protein Accession#
NP_647478.1Gene Name
BIRC7
Gene Alias
KIAP, LIVIN, ML-IAP, MLIAP, RNF50
Gene Description
baculoviral IAP repeat-containing 7
Omim ID
605737Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide. [provided by RefSeq
Other Designations
OTTHUMP00000031536|OTTHUMP00000031537|baculoviral IAP repeat-containing protein 7|kidney inhibitor of apoptosis protein|livin inhibitor of apoptosis|livin inhibitor-of-apoptosis|melanoma inhibitor of apoptosis protein
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Interactome
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