CEP55 purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Cell lysate)
CEP55 MaxPab polyclonal antibody. Western Blot analysis of CEP55 expression in HeLa.
Western Blot (Transfected lysate)
Western Blot analysis of CEP55 expression in transfected 293T cell line (H00055165-T01) by CEP55 MaxPab polyclonal antibody.
Lane 1: CEP55 transfected lysate(51.04 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CEP55 protein.
Immunogen
CEP55 (NP_060601.2, 1 a.a. ~ 464 a.a) full-length human protein.
Sequence
MSSRSTKDLIKSKWGSKPSNSKSETTLEKLKGEIAHLKTSVDEITSGKGKLTDKERHRLLEKIRVLEAEKEKNAYQLTEKDKEIQRLRDQLKARYSTTALLEQLEETTREGERREQVLKALSEEKDVLKQQLSAATSRIAELESKTNTLRLSQTVAPNCFNSSINNIHEMEIQLKDALEKNQQWLVYDQQREVYVKGLLAKIFELEKKTETAAHSLPQQTKKPESEGYLQEEKQKCYNDLLASAKKDLEVERQTITQLSFELSEFRRKYEETQKEVHNLNQLLYSQRRADVQHLEDDRHKTEKIQKLREENDIARGKLEEEKKRSEELLSQVQFLYTSLLKQQEEQTRVALLEQQMQACTLDFENEKLDRQHVQHQLLVILKELRKARNQITQLESLKQLHEFAITEPLVTFQGETENREKVAASPKSPTAALNESLVECPKCNIQYPATEHRDLLVHVEYCSK
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (75); Rat (76)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Cell lysate)
CEP55 MaxPab polyclonal antibody. Western Blot analysis of CEP55 expression in HeLa.Western Blot (Transfected lysate)
Western Blot analysis of CEP55 expression in transfected 293T cell line (H00055165-T01) by CEP55 MaxPab polyclonal antibody.
Lane 1: CEP55 transfected lysate(51.04 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CEP55
Entrez GeneID
55165GeneBank Accession#
NM_018131.3Protein Accession#
NP_060601.2Gene Name
CEP55
Gene Alias
C10orf3, FLJ10540, URCC6
Gene Description
centrosomal protein 55kDa
Omim ID
610000Gene Ontology
HyperlinkOther Designations
OTTHUMP00000020117|up-regulated in colon cancer 6
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Interactome
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Disease
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Publication Reference
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Loss of coiled-coil protein Cep55 impairs neural stem cell abscission and results in p53-dependent apoptosis in developing cortex.
Jessica N Little, Katrina C McNeely, Nadine Michel, Christopher J Bott, Kaela S Lettieri, Madison R Hecht, Sara A Martin, Noelle D Dwyer.
Journal of Neuroscience 2021 Apr; 41(15):3344.
Application：WB-Ce, Mouse, MEFs.
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A truncating mutation in CEP55 is the likely cause of MARCH, a novel syndrome affecting neuronal mitosis.
Frosk P, Arts HH, Philippe J, Gunn CS, Brown EL, Chodirker B, Simard L, Majewski J, Fahiminiya S, Russell C, Liu YP; FORGE Canada Consortium; Canadian Rare Diseases: Models & Mechanisms Network,, Hegele R, Katsanis N, Goerz C, Del Bigio MR, Davis EE.
Journal of Medical Genetics 2017 Jul; 54(7):490.
Application：WB, Human, COS-7 cells.
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Loss of coiled-coil protein Cep55 impairs neural stem cell abscission and results in p53-dependent apoptosis in developing cortex.
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