CLDN2 (Human) Recombinant Protein (P01)
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More Files
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Specification
Product Description
Human CLDN2 full-length ORF ( NP_065117.1, 1 a.a. - 230 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
MASLGLQLVGYILGLLGLLGTLVAMLLPSWKTSSYVGASIVTAVGFSKGLWMECATHSTGITQCDIYSTLLGLPADIQAAQAMMVTSSAISSLACIISVVGMRCTVFCQESRAKDRVAVAGGVFFILGGLLGFIPVAWNLHGILRDFYSPLVPDSMKFEIGEALYLGIISSLFSLIAGIILCFSCSSQRNRSNYYDAYQAQPLATRSSPRPGQPPKVKSEFNSYSLTGYV
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
50.9
Interspecies Antigen Sequence
Mouse (91); Rat (91)
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — CLDN2
Entrez GeneID
9075GeneBank Accession#
NM_020384.2Protein Accession#
NP_065117.1Gene Name
CLDN2
Gene Alias
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Gene Description
claudin 2
Omim ID
300520Gene Ontology
HyperlinkGene Summary
Members of the claudin protein family, such as CLDN2, are expressed in an organ-specific manner and regulate the tissue-specific physiologic properties of tight junctions (Sakaguchi et al., 2002 [PubMed 11934881]).[supplied by OMIM
Other Designations
OTTHUMP00000023793
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Interactome
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Pathway
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Publication Reference
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Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies.
Randall K, Henderson N, Reens J, Eckersley S, Nyström AC, South MC, Balendran CA, Böttcher G, Hughes G, Price SA.
PLoS One 2016 Sep; 11(9):e0162076.
Application：WB, Human, Cell lysates.
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Claudin-2 Expression Levels in Ulcerative Colitis: Development and Validation of an In-Situ Hybridisation Assay for Therapeutic Studies.
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