TLR2 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TLR2 full-length
Host
Human
Theoretical MW (kDa)
86.35
Interspecies Antigen Sequence
Mouse (71); Rat (72)
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TLR2 antibody (H00007097-B01) by Western Blots.
SDS-PAGE Gel
TLR2 transfected lysate.
Western Blot
Lane 1: TLR2 transfected lysate ( 86.35 KDa)
Lane 2: Non-transfected lysate.Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — TLR2
Entrez GeneID
7097GeneBank Accession#
NM_003264.3Protein Accession#
-Gene Name
TLR2
Gene Alias
CD282, TIL4
Gene Description
toll-like receptor 2
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is expressed most abundantly in peripheral blood leukocytes, and mediates host response to Gram-positive bacteria and yeast via stimulation of NF-kappaB. [provided by RefSeq
Other Designations
toll/interleukin 1 receptor-like 4
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Interactome
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Pathway
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Disease
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