SGCD (Human) Recombinant Protein (Q01)
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More Files
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Specification
Product Description
Human SGCD partial ORF ( NP_000328.2, 114 a.a. - 189 a.a.) recombinant protein with GST-tag at N-terminal.
Sequence
ILNDQTKVLTQLITGPKAVEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFK
Host
Wheat Germ (in vitro)
Theoretical MW (kDa)
34.1
Preparation Method
Purification
Glutathione Sepharose 4 Fast Flow
Quality Control Testing
12.5% SDS-PAGE Stained with Coomassie Blue.
Storage Buffer
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
Note
Best use within three months from the date of receipt of this protein.
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Applications
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array
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Gene Info — SGCD
Entrez GeneID
6444GeneBank Accession#
NM_000337Protein Accession#
NP_000328.2Gene Name
SGCD
Gene Alias
35DAG, CMD1L, DAGD, MGC22567, SG-delta, SGCDP, SGD
Gene Description
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
Other Designations
35kD dystrophin-associated glycoprotein|delta-sarcoglycan|dystrophin associated glycoprotein, delta sarcoglycan|placental delta sarcoglycan|sarcoglycan, delta (35kD dystrophin-associated glycoprotein)
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Interactome
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Pathway
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Disease
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