SGCD monoclonal antibody (M01), clone 3G10
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant SGCD.
Immunogen
SGCD (NP_000328.2, 114 a.a. ~ 189 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ILNDQTKVLTQLITGPKAVEAYGKKFEVKTVSGKLLFSADNNEVVVGAERLRVLGAEGTVFPKSIETPNVRADPFK
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.1 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged SGCD is 0.03 ng/ml as a capture antibody.ELISA
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Gene Info — SGCD
Entrez GeneID
6444GeneBank Accession#
NM_000337Protein Accession#
NP_000328.2Gene Name
SGCD
Gene Alias
35DAG, CMD1L, DAGD, MGC22567, SG-delta, SGCDP, SGD
Gene Description
sarcoglycan, delta (35kDa dystrophin-associated glycoprotein)
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is one of the four known components of the sarcoglycan complex, which is a subcomplex of the dystrophin-glycoprotein complex (DGC). DGC forms a link between the F-actin cytoskeleton and the extracellular matrix. This protein is expressed most abundantly in skeletal and cardiac muscle. Mutations in this gene have been associated with autosomal recessive limb-girdle muscular dystrophy and dilated cardiomyopathy. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq
Other Designations
35kD dystrophin-associated glycoprotein|delta-sarcoglycan|dystrophin associated glycoprotein, delta sarcoglycan|placental delta sarcoglycan|sarcoglycan, delta (35kD dystrophin-associated glycoprotein)
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Interactome
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Pathway
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Disease
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