Products

Enzyme-linked Immunoabsorbent Assay

Western Blot (Recombinant protein)

Antibody Production

Protein Array

Entrez GeneID

GeneBank Accession#

Protein Accession#

Gene Name

PSMB2

Gene Alias

HC7-I, MGC104215, MGC126885

Gene Description

proteasome (prosome, macropain) subunit, beta type, 2

Omim ID

Gene Ontology

Gene Summary

The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. [provided by RefSeq

Other Designations

OTTHUMP00000004345|macropain subunit C7-I|multicatalytic endopeptidase complex subunit C7-1|proteasome beta 2 subunit|proteasome component C7-I|proteasome subunit, beta type, 2