NFKBIL2 rabbit monoclonal antibody
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Specification
Product Description
Rabbit monoclonal antibody raised against a human NFKBIL2 peptide using ARM Technology.
Immunogen
A synthetic peptide of human NFKBIL2 is used for rabbit immunization.
Customer or Abnova will decide on the preferred peptide sequence.Host
Rabbit
Library Construction
Non-fusion antibody library from rabbit spleen (ARM Technology).
Expression
Overexpression vector and transfection into 293H cell line.
Reactivity
Human
Purification
Protein A
Isotype
IgG
Quality Control Testing
Antibody reactive against human NFKBIL2 peptide by ELISA and mammalian transfected lysate by Western Blot.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
Deliverable
Up to three rabbit IgG clones of 100 ug each will be delivered to customer.
Note
1. Customer may provide cell or tissue lysate for antibody screening.
2. Rabbit monoclonal antibody generated by ARM technology is amenable to antibody engineering including F(ab)2, IgG, scFv and different Fc and non-Fc conjugates per customer request. -
Applications
Western Blot (Transfected lysate)
ELISA
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Gene Info — NFKBIL2
Entrez GeneID
4796GeneBank Accession#
NFKBIL2Gene Name
NFKBIL2
Gene Alias
FLJ40087, IKBR
Gene Description
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor-like 2
Omim ID
604546Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus. [provided by RefSeq
Other Designations
I-kappa-B-related protein|NF-kappa-B inhibitor-like protein 2
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Interactome
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Disease
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