IL8 monoclonal antibody (M12), clone 4G11
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant IL8.
Immunogen
IL8 (AAH13615, 21 a.a. ~ 99 a.a) full length recombinant protein.
Sequence
EGAVLPRSAKELRCQCIKTYSKPFHPKFIKELRVIESGPHCANTEIIVKLSDGRELCLDPKENWVQRVVEKFLKRAENS
Host
Mouse
Reactivity
Human
Isotype
IgG1 Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (31.69 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
Western Blot (Recombinant protein)
IL8 monoclonal antibody, clone 4G11 ( Cat # H00003576-M12 ) . Western Blot detection against a 8.9 KDa biologically active recombinant human IL-8 ( endothelial-derived ).Immunoprecipitation
Immunoprecipitation of IL8 transfected lysate using anti-IL8 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with IL8 MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — IL8
Entrez GeneID
3576GeneBank Accession#
BC013615Protein Accession#
AAH13615Gene Name
IL8
Gene Alias
CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1
Gene Description
interleukin 8
Omim ID
146930Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the CXC chemokine family. This chemokine is one of the major mediators of the inflammatory response. This chemokine is secreted by several cell types. It functions as a chemoattractant, and is also a potent angiogenic factor. This gene is believed to play a role in the pathogenesis of bronchiolitis, a common respiratory tract disease caused by viral infection. This gene and other ten members of the CXC chemokine gene family form a chemokine gene cluster in a region mapped to chromosome 4q. [provided by RefSeq
Other Designations
T cell chemotactic factor|beta-thromboglobulin-like protein|chemokine (C-X-C motif) ligand 8|emoctakin|granulocyte chemotactic protein 1|lymphocyte-derived neutrophil-activating factor|monocyte-derived neutrophil chemotactic factor|neutrophil-activating p
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Interactome
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Pathway
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Disease
- Acute Disease
- Adenocarcinoma
- Adenomatous Polyps
- Alcoholism
- Alzheimer disease
- Appetite
- Arthritis
- Asthma
- Atherosclerosis
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Publication Reference
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Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome.
Cremon C, Stanghellini V, Barbaro MR, Cogliandro RF, Bellacosa L, Santos J, Vicario M, Pigrau M, Alonso Cotoner C, Lobo B, Azpiroz F, Bruley des Varannes S, Neunlist M, DeFilippis D, Iuvone T, Petrosino S, Di Marzo V, Barbara G.
Alimentary Pharmacology & Therapeutics 2017 Apr; 45(7):909.
Application:WB, Human, Patients with irritable bowel syndrome (IBS).
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Randomised clinical trial: the analgesic properties of dietary supplementation with palmitoylethanolamide and polydatin in irritable bowel syndrome.
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