HYAL1 monoclonal antibody (M01), clone 2H7
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of HYAL1 transfected lysate using anti-HYAL1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HYAL1 MaxPab rabbit polyclonal antibody.
Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HYAL1 is approximately 1ng/ml as a capture antibody.
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Specification
Product Description
Mouse monoclonal antibody raised against a partial recombinant HYAL1.
Immunogen
HYAL1 (NP_009296, 60 a.a. ~ 159 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
ANPGQTFRGPDMTIFYSSQLGTYPYYTPTGEPVFGGLPQNASLIAHLARTFQDILAAIPAPDFSGLAVIDWEAWRPRWAFNWDTKDIYRQRSRALVQAQH
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of HYAL1 transfected lysate using anti-HYAL1 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with HYAL1 MaxPab rabbit polyclonal antibody.Sandwich ELISA (Recombinant protein)
Detection limit for recombinant GST tagged HYAL1 is approximately 1ng/ml as a capture antibody.ELISA
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Gene Info — HYAL1
Entrez GeneID
3373GeneBank Accession#
NM_007312Protein Accession#
NP_009296Gene Name
HYAL1
Gene Alias
HYAL-1, LUCA1, MGC45987, NAT6
Gene Description
hyaluronoglucosaminidase 1
Gene Ontology
HyperlinkGene Summary
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
hyaluronidase 1|plasma hyaluronidase|tumor suppressor LUCA-1
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Interactome
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Pathway
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Disease
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