GBP2 monoclonal antibody (M03), clone 2A10
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More Files
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Specification
Product Description
Mouse monoclonal antibody raised against a full-length recombinant GBP2.
Immunogen
GBP2 (AAH22272, 1 a.a. ~ 481 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MAPEINLPGPMSLIDNTKGQLVVNPEALKILSAITQPVVVVAIVGLYRTGKSYLMNKLAGKKNGFSLGSTVKSHTKGIWMWCVPHPKKPEHTLVLLDTEGLGDIEKGDNENDSWIFALAILLSSTFVYNSMGTINQQAMDQLHYVTELTDRIKANSSPGNNSVDDSADFVSFFPAFVWTLRDFTLELEVDGEPITADDYLELSLKLRKGTDKKSKSFNDPRLCIRKFFPKRKCFVFDWPAPKKYLAHLEQLKEEELNPDFIEQVAEFCSYILSHSNVKTLSGGIPVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVEKAIAHYEQQMGQKVQLPTETLQELLDLHRDSEREAIEVFMKNSFKDVDQMFQRKLGAQLEARRDDFCKQNSKASSDCCMALLQDIFGPLEEDVKQGTFSKPGGYRLFTQKLQELKNKYYQVPRKGIQAKEVLKKYLESKEDVADALLQTDQSLS
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (78.65 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of GBP2 expression in transfected 293T cell line by GBP2 monoclonal antibody (M03), clone 2A10.
Lane 1: GBP2 transfected lysate (Predicted MW: 67.2 KDa).
Lane 2: Non-transfected lysate.
Western Blot (Recombinant protein)
Immunoprecipitation
Immunoprecipitation of GBP2 transfected lysate using anti-GBP2 monoclonal antibody and Protein A Magnetic Bead, and immunoblotted with GBP2 MaxPab rabbit polyclonal antibody.ELISA
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Gene Info — GBP2
Entrez GeneID
2634GeneBank Accession#
BC022272Protein Accession#
AAH22272Gene Name
GBP2
Gene Alias
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Gene Description
guanylate binding protein 2, interferon-inducible
Omim ID
600412Gene Ontology
HyperlinkGene Summary
Interferons are cytokines that have antiviral effects and inhibit tumor cell proliferation. They induce a large number of genes in their target cells, including those coding for the guanylate-binding proteins (GBPs). GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). The protein encoded by this gene is a GTPase that converts GTP to GDP and GMP. [provided by RefSeq
Other Designations
OTTHUMP00000012393
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Interactome
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Disease
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