GBP1 monoclonal antibody (M01), clone 4D10
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Specification
Product Description
Mouse monoclonal antibody raised against a full length recombinant GBP1.
Immunogen
GBP1 (AAH02666, 1 a.a. ~ 592 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Sequence
MASEIHMTGPMCLIENTNGRLMANPEALKILSAITQPMVVVAIVGLYRTGKSYLMNKLAGKKKGFSLGSTVQSHTKGIWMWCVPHPKKPGHILVLLDTEGLGDVEKGDNQNDSWIFALAVLLSSTFVYNSIGTINQQAMDQLYYVTELTHRIRSKSSPDENENEVEDSADFVSFFPDFVWTLRDFSLDLEADGQPLTPDEYLTYSLKLKKGTSQKDETFNLPRLCIRKFFPKKKCFVFDRPVHRRKLAQLEKLQDEELDPEFVQQVADFCSYIFSNSKTKTLSGGIQVNGPRLESLVLTYVNAISSGDLPCMENAVLALAQIENSAAVQKAIAHYEQQMGQKVQLPTESLQELLDLHRDSEREAIEVFIRSSFKDVDHLFQKELAAQLEKKRDDFCKQNQEASSDRCSGLLQVIFSPLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAILQTDQTLTEKEKEIEVERVKAESAQASAKMLQEMQRKNEQMMEQKERSYQEHLKQLTEKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQKESRIMKNEIQDLQTKMRRRKACTIS
Host
Mouse
Reactivity
Human
Isotype
IgG2a Kappa
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (90.86 KDa) .
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Tissue lysate)
GBP1 monoclonal antibody (M01), clone 4D10. Western Blot analysis of GBP1 expression in human spleen.Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
Immunoperoxidase of monoclonal antibody to GBP1 on formalin-fixed paraffin-embedded human pancreas. [antibody concentration 1.5 ug/ml]ELISA
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Gene Info — GBP1
Entrez GeneID
2633GeneBank Accession#
BC002666Protein Accession#
AAH02666Gene Name
GBP1
Gene Alias
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Gene Description
guanylate binding protein 1, interferon-inducible, 67kDa
Omim ID
600411Gene Ontology
HyperlinkGene Summary
Guanylate binding protein expression is induced by interferon. Guanylate binding proteins are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. [provided by RefSeq
Other Designations
OTTHUMP00000012352
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Interactome
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Disease
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Publication Reference
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A signature of immune function genes associated with recurrence-free survival in breast cancer patients.
Ascierto ML, Kmieciak M, Idowu MO, Manjili R, Zhao Y, Grimes M, Dumur C, Wang E, Ramakrishnan V, Wang XY, Bear HD, Marincola FM, Manjili MH.
Breast Cancer Research and Treatment 2012 Feb; 131(3):871.
Application:IHC-P, Human, Human breast cancer .
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A signature of immune function genes associated with recurrence-free survival in breast cancer patients.
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