DSCR1 polyclonal antibody (A02)

Catalog # H00001827-A02

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Price

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Size:50 uL
Price: USD $ 243.00
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Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
  • Specification

    Product Description

    Mouse polyclonal antibody raised against a full-length recombinant DSCR1.

    Immunogen

    DSCR1 (AAH02864, 1 a.a. ~ 197 a.a) full-length recombinant protein with GST tag.

    Sequence

    MEEVDLRDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNPDKQFLISPPASPPVGWKQVEDATPVINYDLLYAISKLGPGEKYELHAATDTTPSVVVHVCESDQEKEEEEEMERMRRPKPKIIQTRRPEYTQIHLS

    Host

    Mouse

    Reactivity

    Human

    Quality Control Testing

    Antibody Reactive Against Recombinant Protein.

    Storage Buffer

    50 % glycerol

    Storage Instruction

    Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

  • Applications

    ELISA

  • Gene Info — RCAN1

    Entrez GeneID

    1827

    GeneBank Accession#

    BC002864

    Protein Accession#

    AAH02864

    Gene Name

    RCAN1

    Gene Alias

    ADAPT78, CSP1, DSC1, DSCR1, MCIP1, RCN1

    Gene Description

    regulator of calcineurin 1

    Omim ID

    602917

    Gene Ontology

    Hyperlink

    Gene Summary

    The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq

    Other Designations

    Down syndrome candidate region 1|Down syndrome critical region gene 1|calcipressin 1|calcium and oxidant-inducible mRNA|modulatory calcineurin-interacting protein 1|myocyte-enriched calcineurin-interacting protein 1|near DSCR proline-rich protein

  • Interactome
  • Disease
Contact Info
  • +1-909-264-1399
    +1-909-992-0619
    Toll Free : +1-877-853-6098
  • +1-909-992-3401
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