DHCR24 (Human) IP-WB Antibody Pair
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More Files
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Immunoprecipitation of DHCR24 transfected lysate using rabbit polyclonal anti-DHCR24 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DHCR24.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (96%); Rat (96%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of DHCR24 transfected lysate using rabbit polyclonal anti-DHCR24 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-DHCR24.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-DHCR24 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-DHCR24 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — DHCR24
Entrez GeneID
1718Gene Name
DHCR24
Gene Alias
KIAA0018, Nbla03646, SELADIN1, seladin-1
Gene Description
24-dehydrocholesterol reductase
Gene Ontology
HyperlinkGene Summary
This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq
Other Designations
3 beta-hydroxysterol delta 24-reductase|OTTHUMP00000011685|diminuto/dwarf1 homolog|putative protein product of Nbla03646|selective AD indicator 1
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Interactome
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Pathway
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Disease
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