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BIOtech
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DHCR24 MaxPab rabbit polyclonal antibody (D01)MaxPab

  • Catalog # : H00001718-D01
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Rabbit polyclonal antibody raised against a full-length human DHCR24 protein.
  • Immunogen:
  • DHCR24 (NP_055577.1, 1 a.a. ~ 516 a.a) full-length human protein.
  • Sequence:
  • MEPAVSLAVCALLFLLWVRLKGLEFVLIHQRWVFVCLFLLPLSLIFDIYYYVRAWVVFKLSSAPRLHEQRVRDIQKQVREWKEQGSKTFMCTGRPGWLTVSLRVGKYKKTHKNIMINLMDILEVDTKKQIVRVEPLVTMGQVTALLTSIGWTLPVLPELDDLTVGGLIMGTGIESSSHKYGLFQHICTAYELVLADGSFVRCTPSENSDLFYAVPWSCGTLGFLVAAEIRIIPAKKYVKLRFEPVRGLEAICAKFTHESQRQENHFVEGLLYSLDEAVIMTGVMTDEAEPSKLNSIGNYYKPWFFKHVENYLKTNREGLEYIPLRHYYHRHTRSIFWELQDIIPFGNNPIFRYLFGWMVPPKISLLKLTQGETLRKLYEQHHVVQDMLVPMKCLQQALHTFQNDIHVYPIWLCPFILPSQPGLVHPKGNEAELYIDIGAYGEPRVKHFEARSCMRQLEKFVRSVHGFQMLYADCYMNREEFWEMFDGSLYHKLREKLGCQDAFPEVYDKICKAARH
  • Host:
  • Rabbit
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody reactive against mammalian transfected lysate.
  • Storage Buffer:
  • No additive
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • Western Blot analysis of DHCR24 expression in transfected 293T cell line (H00001718-T01) by DHCR24 MaxPab polyclonal antibody.

    Lane 1: DHCR24 transfected lysate(60.10 KDa).
    Lane 2: Non-transfected lysate.
  • Protocol Download
  • Immunoprecipitation
  • Immunoprecipitation
  • Immunoprecipitation of DHCR24 transfected lysate using anti-DHCR24 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with DHCR24 purified MaxPab mouse polyclonal antibody (B01P) (H00001718-B01P).
  • Protocol Download
  • Detection Antibody
  • Application Image
  • Western Blot (Transfected lysate)
  • Western Blot (Transfected lysate)
  • enlarge
  • Detection Antibody
  • Gene Information
  • Entrez GeneID:
  • 1718
  • Gene Name:
  • DHCR24
  • Gene Alias:
  • KIAA0018,Nbla03646,SELADIN1,seladin-1
  • Gene Description:
  • 24-dehydrocholesterol reductase
  • Gene Summary:
  • This gene encodes a flavin adenine dinucleotide (FAD)-dependent oxidoreductase which catalyzes the reduction of the delta-24 double bond of sterol intermediates during cholesterol biosynthesis. The protein contains a leader sequence that directs it to the endoplasmic reticulum membrane. Missense mutations in this gene have been associated with desmosterolosis. Also, reduced expression of the gene occurs in the temporal cortex of Alzheimer disease patients and overexpression has been observed in adrenal gland cancer cells. [provided by RefSeq
  • Other Designations:
  • 3 beta-hydroxysterol delta 24-reductase,OTTHUMP00000011685,diminuto/dwarf1 homolog,putative protein product of Nbla03646,selective AD indicator 1
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