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Last updated: 2015/11/29

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CSE1L (Human) Recombinant Protein (P01)

  • Catalog # : H00001434-P01
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  • Specification
  • Product Description:
  • Human CSE1L full-length ORF ( ENSP00000343253, 1 a.a. - 195 a.a.) recombinant protein with GST-tag at N-terminal.
  • Sequence:
  • Host:
  • Wheat Germ (in vitro)
  • Theoretical MW (kDa):
  • 49.1
  • Purification:
  • Glutathione Sepharose 4 Fast Flow
  • Quality Control Testing:
  • 12.5% SDS-PAGE Stained with Coomassie Blue.

    QC Testing of H00001434-P01
  • Storage Buffer:
  • 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
  • Storage Instruction:
  • Store at -80°C. Aliquot to avoid repeated freezing and thawing.
  • Note:
  • Best use within three months from the date of receipt of this protein.
  • Applications
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Application Image
  • Enzyme-linked Immunoabsorbent Assay
  • Western Blot (Recombinant protein)
  • Antibody Production
  • Protein Array
  • Gene Information
  • Entrez GeneID:
  • 1434
  • Gene Name:
  • CSE1L
  • Gene Alias:
  • CAS,CSE1,MGC117283,MGC130036,MGC130037,XPO2
  • Gene Description:
  • CSE1 chromosome segregation 1-like (yeast)
  • Gene Summary:
  • Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. [provided by RefSeq
  • Other Designations:
  • CSE1 chromosome segregation 1-like protein,OTTHUMP00000043373,cellular apoptosis susceptibility protein,chromosome segregation 1-like,importin-alpha re-exporter
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