CRX polyclonal antibody (A01)
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More Files
- More Functions
Western Blot detection against Immunogen (36.56 KDa) .
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Specification
Product Description
Mouse polyclonal antibody raised against a partial recombinant CRX.
Immunogen
CRX (NP_000545, 1 a.a. ~ 95 a.a) partial recombinant protein with GST tag.
Sequence
MMAYMNPGPHYSVNALALSGPSVDLMHQAVPYPSAPRKQRRERTTFTRSQLEELEALFAKTQYPDVYAREEVALKINLPESRVQVWFKNRRAKCR
Host
Mouse
Reactivity
Human
Interspecies Antigen Sequence
Mouse (98); Rat (99)
Quality Control Testing
Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (36.56 KDa) .
Storage Buffer
50 % glycerol
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Recombinant protein)
ELISA
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Gene Info — CRX
Entrez GeneID
1406GeneBank Accession#
NM_000554Protein Accession#
NP_000545Gene Name
CRX
Gene Alias
CORD2, CRD, LCA7, OTX3
Gene Description
cone-rod homeobox
Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a photoreceptor-specific transcription factor which plays a role in the differentiation of photoreceptor cells. This homeodomain protein is necessary for the maintenance of normal cone and rod function. Mutations in this gene are associated with photoreceptor degeneration, Leber congenital amaurosis type III and the autosomal dominant cone-rod dystrophy 2. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined. [provided by RefSeq
Other Designations
cone-rod homeobox protein|orthodenticle homeobox 3
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Interactome
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Disease
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Publication Reference
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Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cells.
Jonathan Eintracht, Philippa Harding, Dulce Lima Cunha, Mariya Moosajee.
F1000Research 2022 Mar; 11:324.
Application：IF, Human, Optic vesicle (Human induced pluripotent stem cell).
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Efficient embryoid-based method to improve generation of optic vesicles from human induced pluripotent stem cells.
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