CNTF purified MaxPab mouse polyclonal antibody (B01P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CNTF expression in transfected 293T cell line (H00001270-T01) by CNTF MaxPab polyclonal antibody.
Lane 1: CNTF transfected lysate(22 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CNTF protein.
Immunogen
CNTF (NP_000605.1, 1 a.a. ~ 200 a.a) full-length human protein.
Sequence
MAFTEHSPLTPHRRDLCSRSIWLARKIRSDLTALTESYVKHQGLNKNINLDSADGMPVASTDQWSELTEAERLQENLQAYRTFHVLLARLLEDQQVHFTPTEGDFHQAIHTLLLQVAAFAYQIEELMILLEYKIPRNEADGMPINVGDGGLFEKKLWGLKVLQELSQWTVRSIHDLRFISSHQTGIPARGSHYIANNKKM
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CNTF expression in transfected 293T cell line (H00001270-T01) by CNTF MaxPab polyclonal antibody.
Lane 1: CNTF transfected lysate(22 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CNTF
Entrez GeneID
1270GeneBank Accession#
NM_000614Protein Accession#
NP_000605.1Gene Name
CNTF
Gene Alias
HCNTF
Gene Description
ciliary neurotrophic factor
Omim ID
118945Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The protein is a potent survival factor for neurons and oligodendrocytes and may be relevant in reducing tissue destruction during inflammatory attacks. A mutation in this gene, which results in aberrant splicing, leads to ciliary neurotrophic factor deficiency, but this phenotype is not causally related to neurologic disease. A read-through transcript variant composed of ZFP91 and CNTF sequence has been identified, but it is thought to be non-coding. Read-through transcription of ZFP91 and CNTF has also been observed in mouse. [provided by RefSeq
Other Designations
OTTHUMP00000174731
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Interactome
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Pathway
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Disease
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