TPP1 (Human) IP-WB Antibody Pair
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More Files
- More Functions
Immunoprecipitation of TPP1 transfected lysate using rabbit polyclonal anti-TPP1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TPP1.
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Specification
Product Description
This IP-WB antibody pair set comes with one antibody for immunoprecipitation and another to detect the precipitated protein in western blot.
Reactivity
Human
Interspecies Antigen Sequence
Mouse (88%); Rat (87%)
Quality Control Testing
Immunoprecipitation-Western Blot (IP-WB)
Immunoprecipitation of TPP1 transfected lysate using rabbit polyclonal anti-TPP1 and Protein A Magnetic Bead (U0007), and immunoblotted with mouse purified polyclonal anti-TPP1.
Supplied Product
Antibody pair set content:
1. Antibody pair for IP: rabbit polyclonal anti-TPP1 (300 ul)
2. Antibody pair for WB: mouse purified polyclonal anti-TPP1 (50 ug)
Storage Instruction
Store reagents of the antibody pair set at -20°C or lower. Please aliquot to avoid repeated freeze thaw cycle. Reagents should be returned to -20°C storage immediately after use.
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Applications
Immunoprecipitation-Western Blot
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Gene Info — TPP1
Entrez GeneID
1200Gene Name
TPP1
Gene Alias
CLN2, GIG1, LPIC, MGC21297
Gene Description
tripeptidyl peptidase I
Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activity. It is synthesized as a catalytically-inactive enzyme which is activated and auto-proteolyzed upon acidification. Mutations in this gene result in late-infantile neuronal ceroid lipofuscinosis, which is associated with the failure to degrade specific neuropeptides and a subunit of ATP synthase in the lysosome. [provided by RefSeq
Other Designations
ceroid-lipofuscinosis, neuronal 2, late infantile (Jansky-Bielschowsky disease)|growth-inhibiting protein 1|lysosomal pepstatin insensitive protease|tripeptidyl aminopeptidase|tripeptidyl-peptidase I
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Interactome
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Pathway
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Disease
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