CDKN1B purified MaxPab mouse polyclonal antibody (B03P)
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More Files
- More Functions
Western Blot (Transfected lysate)
Western Blot analysis of CDKN1B expression in transfected 293T cell line (H00001027-T02) by CDKN1B MaxPab polyclonal antibody.
Lane 1: CDKN1B transfected lysate(21.78 KDa).
Lane 2: Non-transfected lysate.
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Specification
Product Description
Mouse polyclonal antibody raised against a full-length human CDKN1B protein.
Immunogen
CDKN1B (ENSP00000228872, 1 a.a. ~ 198 a.a) full-length human protein.
Sequence
MSNVRVSNGSPSLERMDARQAEHPKPSACRNLFGPVDHEELTRDLEKHCRDMEEASQRKWNFDFQNHKPLEGKYEWQEVEKGSLPEFYYRPPRPPKGACKVPAQESQDVSGSRPAAPLIGAPANSEDTHLVDPKTDPSDSQTGLAEQCAGIRKRPATDDSSTQNKRANRTEENVSDGSPNAGSVEQTPKKPGLRRRQT
Host
Mouse
Reactivity
Human
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
In 1x PBS, pH 7.4
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot (Transfected lysate)
Western Blot analysis of CDKN1B expression in transfected 293T cell line (H00001027-T02) by CDKN1B MaxPab polyclonal antibody.
Lane 1: CDKN1B transfected lysate(21.78 KDa).
Lane 2: Non-transfected lysate.
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Gene Info — CDKN1B
Entrez GeneID
1027GeneBank Accession#
NM_004064Protein Accession#
ENSP00000228872Gene Name
CDKN1B
Gene Alias
CDKN4, KIP1, MEN1B, MEN4, P27KIP1
Gene Description
cyclin-dependent kinase inhibitor 1B (p27, Kip1)
Gene Ontology
HyperlinkGene Summary
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq
Other Designations
cyclin-dependent kinase inhibitor 1B
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Interactome
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Pathway
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Disease
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