TNFRSF7 293T Cell Transient Overexpression Lysate(Denatured)
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More Files
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Western Blot
Lane 1: CD27 transfected lysate ( 29.2 KDa)
Lane 2: Non-transfected lysate.
SDS-PAGE Gel
CD27 transfected lysate.
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Specification
Transfected Cell Line
293T
Plasmid
pCMV-TNFRSF7 full-length
Host
Human
Theoretical MW (kDa)
28.71
Quality Control Testing
Transient overexpression cell lysate was tested with Anti-TNFRSF7 antibody (H00000939-B01) by Western Blots.
Western Blot
Lane 1: CD27 transfected lysate ( 29.2 KDa)
Lane 2: Non-transfected lysate.SDS-PAGE Gel
CD27 transfected lysate.
Storage Buffer
1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
Storage Instruction
Store at -80°C. Aliquot to avoid repeated freezing and thawing.
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Applications
Western Blot
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Gene Info — CD27
Entrez GeneID
939GeneBank Accession#
NM_001242Protein Accession#
NP_001233Gene Name
CD27
Gene Alias
MGC20393, S152, T14, TNFRSF7, Tp55
Gene Description
CD27 molecule
Omim ID
186711Gene Ontology
HyperlinkGene Summary
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq
Other Designations
CD27 antigen|CD27L receptor|T cell activation antigen CD27|T cell antivation antigen S152|tumor necrosis factor receptor superfamily, member 7
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Interactome
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Pathway
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Disease
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