RUNX3 MaxPab rabbit polyclonal antibody (D01)
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More Files
- More Functions
Immunoprecipitation
Immunoprecipitation of RUNX3 transfected lysate using anti-RUNX3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with RUNX3 purified MaxPab mouse polyclonal antibody (B01P) (H00000864-B01P).
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Specification
Product Description
Rabbit polyclonal antibody raised against a full-length human RUNX3 protein.
Immunogen
RUNX3 (AAH13362.1, 1 a.a. ~ 429 a.a) full-length human protein.
Sequence
MASNSIFDSFPTYSPTFIRDPSTSRRFTPPSPAFPCGGGGGKMGENSGALSAQAAVGPGGRARPEVRSMVDVLADHAGELVRTDSPNFLCSVLPSHWRCNKTLPVAFKVVALGDVPDGTVVTVMAGNDENYSAELRNASAVMKNQVARFNDLRFVGRSGRGKSFTLTITVFTNPTQVATYHRAIKVTVDGPREPRRHRQKLEDQTKPFPDRFGDLERLRMRVTPSTPSPRGSLSTTSHFSSQPQTPIQGTSELNPFSDPRQFDRSFPTLPTLTESRFPDPRMHYPGAMSAAFPYSATPSGTSISSLSVAGMPATSRFHHTYLPPPYPGAPQNQSGPFQANPSPYHLYYGTSSGSYQFSMVAGSSSGGDRSPTRMLASCTSSAASVAAGNLMNPSLGGQSDGVEADGSHSNSPTALSTPGRMDEAVWRPY
Host
Rabbit
Reactivity
Human
Interspecies Antigen Sequence
Rat (91)
Quality Control Testing
Antibody reactive against mammalian transfected lysate.
Storage Buffer
No additive
Storage Instruction
Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
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Applications
Immunoprecipitation
Immunoprecipitation of RUNX3 transfected lysate using anti-RUNX3 MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead, and immunoblotted with RUNX3 purified MaxPab mouse polyclonal antibody (B01P) (H00000864-B01P). -
Gene Info — RUNX3
Entrez GeneID
864GeneBank Accession#
NM_001031680.2Protein Accession#
AAH13362.1Gene Name
RUNX3
Gene Alias
AML2, CBFA3, FLJ34510, MGC16070, PEBP2aC
Gene Description
runt-related transcription factor 3
Omim ID
600210Gene Ontology
HyperlinkGene Summary
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
Other Designations
OTTHUMP00000003370|OTTHUMP00000003371|PEA2 alpha C|PEBP2 alpha C|acute myeloid leukemia gene 2|core-binding factor, runt domain, alpha subunit 3|polyomavirus enhancer-binding protein 2 alpha C subunit|transcription factor AML2
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Interactome
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Disease
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