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Last updated: 2015/3/29
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C4B polyclonal antibody (A02)

  • Catalog # : H00000721-A02
  • Visit Frequency :
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  • Specification
  • Product Description:
  • Mouse polyclonal antibody raised against a partial recombinant C4B.
  • Immunogen:
  • C4B (NP_000343, 774 a.a. ~ 873 a.a) partial recombinant protein with GST tag.
  • Sequence:
  • VRSFFPENWLWRVETVDRFQILTLWLPDSLTTWEIHGLSLSKTKGLCVATPVQLRVFREFHLHLRLPMSVRRFEQLELRPVLYNYLDKNLTVSVHVSPVE
  • Host:
  • Mouse
  • Reactivity:
  • Human
  • Quality Control Testing:
  • Antibody Reactive Against Recombinant Protein.

    QC Testing of H00000721-A02
    Western Blot detection against Immunogen (37.11 KDa) .
  • Storage Buffer:
  • 50 % glycerol
  • Storage Instruction:
  • Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
  • Applications
  • ELISA
  • Application Image
  • Western Blot (Recombinant protein)
  • ELISA
  • Gene Information
  • Entrez GeneID:
  • 721
  • Gene Name:
  • C4B
  • Gene Alias:
  • C4A,C4A13,C4A91,C4B1,C4B12,C4B2,C4B3,C4B5,C4F,CH,CO4,CPAMD3,FLJ60561,MGC164979
  • Gene Description:
  • complement component 4B (Chido blood group)
  • Gene Summary:
  • This gene encodes the basic form of complement factor 4, part of the classical activation pathway. The protein is expressed as a single chain precursor which is proteolytically cleaved into a trimer of alpha, beta, and gamma chains prior to secretion. The trimer provides a surface for interaction between the antigen-antibody complex and other complement components. The alpha chain may be cleaved to release C4 anaphylatoxin, a mediator of local inflammation. Deficiency of this protein is associated with systemic lupus erythematosus. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. Varying haplotypes of this gene cluster exist, such that individuals may have 1, 2, or 3 copies of this gene. In addition, this gene exists as a long form and a short form due to the presence or absence of a 6.4 kb endogenous HERV-K retrovirus in intron 9. [provided by RefSeq
  • Other Designations:
  • Chido form of C4,OTTHUMP00000029269,basic C4,complement C4B1a,complement component 4B,complement component 4B (Childo blood group)
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